Research-only — no human approvalAlso: Epitalon, Epithalamin

Epithalon Dosage Chart

Pulsed-course protocols (10–20 days, repeated twice yearly), reconstitution math, and the limits of the available evidence.

Written by
Megan Williams
Editor-in-Chief
Fact-checked by
Brian Williams
Co-founder & Research Editor
Last updated
April 25, 2026

Fact-checking at PeptideProbe is editorial, not clinical. Our editors check claims, dosing figures, and trial results against primary sources; they are not licensed clinicians and do not provide medical review. Nothing here is medical advice — talk to a qualified healthcare provider before starting any therapy.

Educational tool — not medical advice. This calculator provides estimates based on population averages and published trial data. Outputs are not clinical recommendations and do not replace evaluation by a qualified prescriber. Do not start, stop, or change a peptide therapy based on the result of this tool.

Epithalon is a synthetic tetrapeptide based on Khavinson's Russian gerontology research at the St. Petersburg Institute of Bioregulation. Clinics and vendors commonly present Epithalon as short pulsed courses (10–20 days) repeated periodically rather than continuous use, but the cited PubMed paper is cell-culture work, not a human protocol. Western validation of the original telomerase and longevity claims is limited.

Epithalon at a Glance

Typical dose5–10 mg subQ daily (clinic/vendor convention)
Course length10–20 days continuous (not source-derived)
Course frequency2× per year (every 6 months; clinic/vendor convention)
RouteSubcutaneous (most common); intranasal preparations exist
FDA statusNot FDA-approved. Russian gerontology research basis; Western validation limited.
Common vial size50 mg or 100 mg lyophilized powder

Epithalon Reconstitution Chart

How vial size, bacteriostatic water volume, and insulin-syringe units convert for Epithalon. Use this to translate a prescribed mcg or mg dose into a syringe measurement.

Vial sizeBac waterConcentrationDose → insulin-syringe units (U-100)
50 mg5 mL10 mg/mL (1 mg per 0.1 mL)
  • 5 mg50 units (0.5 mL)
  • 10 mg100 units (1 mL)
100 mg5 mL20 mg/mL (2 mg per 0.1 mL)
  • 5 mg25 units
  • 10 mg50 units (0.5 mL)

Epithalon Dosing by Use Case

Commonly cited protocols vary by what Epithalon is being used for. The table below summarizes typical ranges reported in clinical practice and published literature.

Use caseTypical doseFrequencyCycle lengthNotes
Longevity / wellness (pulsed clinic convention)5–10 mgOnce daily10–20 day course, repeated 2× per yearPulsed-course pattern is clinic/vendor convention; the cited paper is in-vitro cell-culture work.

Where these numbers come from

The cited PubMed paper is an in-vitro study of Epithalon in human fetal pulmonary fibroblasts, reporting telomere/telomerase-related cell-culture effects. It does not test injected 5-10 mg human doses, 10-20 day courses, twice-yearly cycling, adult longevity outcomes, or clinical safety. The protocol shown is clinic/vendor convention, not a dose derived from that paper or from an FDA label.

Use with caution

Epithalon's adult pulsed-use safety claims are practice-based; long-term effects in Western populations are not validated.

  • Clinics commonly describe injection-site reactions as the main side effect, but the cited cell-culture paper does not establish human tolerability.
  • The cited telomere signal is from human fetal fibroblasts in vitro; it is not human longevity evidence.
  • Long-term safety beyond several pulsed cycles is not well-characterized.
  • Not FDA-approved.
Do not use if
  • Active or recent malignancy (theoretical concern with telomerase activation claims)
  • Pregnancy or breastfeeding

Epithalon Dosing FAQ

The short-course pattern is clinic/vendor convention, not something established by the cited cell-culture paper. It should be read as a common protocol format rather than a validated biological reset schedule.

This chart cites in-vitro fetal fibroblast telomere work, not a human or animal lifespan trial. Human longevity data does not exist. Treat anti-aging claims as hypothesized, not validated.

Sources

Related Dosage Charts

Where to get Epithalon with a prescription

Epithalon requires a prescription and medical supervision. Each service below states that a licensed provider reviews your intake and prescribes through a US compounding pharmacy where appropriate. Those are the companies’ own descriptions of how they operate, not findings of ours. Compounded medications are not FDA-approved, and a consultation does not guarantee a prescription.

Some telehealth links below are affiliate links. If you buy through them, we may earn a commission at no extra cost to you. Commission never affects which products or clinics we list, how they are ordered, or what we say about them — see our editorial policy.

HealthRx — telehealth consultationAd

Says a board-certified physician reviews each intake and prescribes through a licensed 503A compounding pharmacy where appropriate, and lists a LegitScript certification. Compounded medications are not FDA-approved.

We are not a clinic and do not prescribe. Listing a service here is not a clinical endorsement of it, and you should confirm licensure and pharmacy sourcing yourself before treatment.

Want the full Epithalon guide?

Mechanism, clinical evidence, side effects, costs, and provider listings for Epithalon therapy.

Medical Disclaimer: This content is for informational purposes only and should not be considered medical advice. Always consult with a qualified healthcare provider before beginning any peptide therapy treatment.