Epitalon Dosage Chart
Pulsed-course protocols (10–20 days, repeated twice yearly), reconstitution math, and the limits of the available evidence.
Educational tool — not medical advice. This calculator provides estimates based on population averages and published trial data. Outputs are not clinical recommendations and do not replace evaluation by a qualified prescriber. Do not start, stop, or change a peptide therapy based on the result of this tool.
Epitalon is a synthetic tetrapeptide based on Khavinson's Russian gerontology research at the St. Petersburg Institute of Bioregulation. The signature feature of Epitalon protocols is short pulsed courses (10–20 days) repeated periodically rather than continuous use. Western validation of the original telomerase and longevity claims is limited.
Epitalon at a Glance
| Typical dose | 5–10 mg subQ daily |
|---|---|
| Course length | 10–20 days continuous |
| Course frequency | 2× per year (every 6 months) |
| Route | Subcutaneous (most common); intranasal preparations exist |
| FDA status | Not FDA-approved. Russian gerontology research basis; Western validation limited. |
| Common vial size | 50 mg or 100 mg lyophilized powder |
Epitalon Reconstitution Chart
How vial size, bacteriostatic water volume, and insulin-syringe units convert for Epitalon. Use this to translate a prescribed mcg or mg dose into a syringe measurement.
| Vial size | Bac water | Concentration | Dose → insulin-syringe units (U-100) |
|---|---|---|---|
| 50 mg | 5 mL | 10 mg/mL (1 mg per 0.1 mL) |
|
| 100 mg | 5 mL | 20 mg/mL (2 mg per 0.1 mL) |
|
Epitalon Dosing by Use Case
Commonly cited protocols vary by what Epitalon is being used for. The table below summarizes typical ranges reported in clinical practice and published literature.
| Use case | Typical dose | Frequency | Cycle length | Notes |
|---|---|---|---|---|
| Anti-aging / longevity (pulsed) | 5–10 mg | Once daily | 10–20 day course, repeated 2× per year | Pulsed-course pattern is the signature Khavinson protocol — not continuous use. |
Epitalon has minimal reported acute toxicity but its long-term effects in Western populations are not validated.
- •Reported side effects in practice are minimal — injection-site reactions are the most common.
- •Original telomerase and longevity claims come from Russian research that has not been independently replicated at scale in Western institutions.
- •Long-term safety beyond several pulsed cycles is not well-characterized.
- •Not FDA-approved.
- •Active or recent malignancy (theoretical concern with telomerase activation claims)
- •Pregnancy or breastfeeding
Epitalon Dosing FAQ
Khavinson's protocol design is based on a 'biological reset' rationale — short pulsed courses are theorized to reset pineal and aging signaling rather than continuously stimulate it. Whether this is mechanistically correct or simply a heuristic is debated.
Russian rodent studies report lifespan extension; Western replication at scale has not been published. Human longevity data does not exist. Treat anti-aging claims as hypothesized, not validated.
Sources
Related Dosage Charts
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Mechanism, clinical evidence, side effects, costs, and provider listings for Epitalon therapy.
See Epitalon guideMedical Disclaimer: This content is for informational purposes only and should not be considered medical advice. Always consult with a qualified healthcare provider before beginning any peptide therapy treatment.