5-Amino-1MQ Therapy: Complete Guide
5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in fat cell metabolism and NAD+ regulation. It is not a peptide, though it is sold alongside them. Interest comes from preclinical work in which NNMT inhibition reduced fat mass in obese mice. There are no completed human clinical trials, and it is not approved for any use.
Fact-checking at PeptideProbe is editorial, not clinical. Our editors check claims, dosing figures, and trial results against primary sources; they are not licensed clinicians and do not provide medical review. Nothing here is medical advice — talk to a qualified healthcare provider before starting any therapy.
What is 5-Amino-1MQ?
5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in fat cell metabolism and NAD+ regulation. It is not a peptide, though it is sold alongside them. Interest comes from preclinical work in which NNMT inhibition reduced fat mass in obese mice. There are no completed human clinical trials, and it is not approved for any use.
How 5-Amino-1MQ Works
5-Amino-1MQ works through specific biological pathways to produce its therapeutic effects. Consult with a qualified provider for detailed information about how this peptide therapy works for your specific condition.
Benefits & Uses
Preclinical only. Rodent studies have reported reduced adipose tissue and improved metabolic markers. None of this has been demonstrated in humans, and animal metabolic findings translate poorly.
Clinical Evidence & Research
Clinical research on 5-Amino-1MQ continues to evolve. 5-Amino-1MQ has been studied in preclinical and clinical settings. Speak with your provider about the current evidence base.
Side Effects & Safety
Not characterised in humans. Because no clinical trials have been completed, the side effect profile, safe dose range, and long-term effects are all unknown.
Dosing & Administration
Dosing protocols for 5-Amino-1MQ should be determined by a qualified healthcare provider based on your individual health profile, treatment goals, and response to therapy. Self-dosing without medical supervision is not recommended.
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Browse Providers5-Amino-1MQ FAQ
Preclinical only. Rodent studies have reported reduced adipose tissue and improved metabolic markers. None of this has been demonstrated in humans, and animal metabolic findings translate poorly.
Costs vary by provider and location. Contact providers directly for current pricing.
5-Amino-1MQ has an FDA status of "Research". It is currently used in research and clinical settings. Consult with a qualified provider about its regulatory status and appropriate use.
Not characterised in humans. Because no clinical trials have been completed, the side effect profile, safe dose range, and long-term effects are all unknown.
PeptideProbe lists 0 providers offering 5-Amino-1MQ therapy. Use our directory to search by location, filter by telehealth availability, and compare providers.
What 5-Amino-1MQ is used for
Each of these reviews the evidence for that goal, including where it is weaker than the marketing suggests.
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Medical Disclaimer: This content is for informational purposes only and should not be considered medical advice. Always consult with a qualified healthcare provider before beginning any peptide therapy treatment.