Hexarelin Dosage Chart
Short-cycle protocol designed around receptor desensitization, with cortisol and prolactin caveats that distinguish hexarelin from ipamorelin.
Educational tool — not medical advice. This calculator provides estimates based on population averages and published trial data. Outputs are not clinical recommendations and do not replace evaluation by a qualified prescriber. Do not start, stop, or change a peptide therapy based on the result of this tool.
Hexarelin is a potent ghrelin-receptor agonist with one of the strongest single-pulse GH releases among the GH secretagogues. Its potency comes with a cost: cortisol and prolactin elevation at higher doses, and rapid receptor desensitization. Cycles are typically short and well-spaced.
Hexarelin at a Glance
| Typical dose | 100 mcg subQ |
|---|---|
| Frequency | 1–2× per day |
| Cycle length | 4 weeks on, 4 weeks off (short cycles to manage desensitization) |
| Typical max | 200–300 mcg/day |
| FDA status | Not FDA-approved. Compounded. |
| Source quality | Small clinical trials in cardiac patients (1990s); off-label use is practitioner-derived. |
Hexarelin Reconstitution Chart
How vial size, bacteriostatic water volume, and insulin-syringe units convert for Hexarelin. Use this to translate a prescribed mcg or mg dose into a syringe measurement.
| Vial size | Bac water | Concentration | Dose → insulin-syringe units (U-100) |
|---|---|---|---|
| 5 mg | 2.5 mL | 2 mg/mL (200 mcg per 0.1 mL) |
|
Hexarelin Dosing by Use Case
Commonly cited protocols vary by what Hexarelin is being used for. The table below summarizes typical ranges reported in clinical practice and published literature.
| Use case | Typical dose | Frequency | Cycle length | Notes |
|---|---|---|---|---|
| GH stimulation (high potency, short cycle) | 100 mcg | 1–2× daily | 4 weeks on, 4 weeks off | Receptor desensitization develops with continuous use; short cycles preserve responsiveness. |
Stacking Hexarelin
Hexarelin is rarely stacked because of its potency and cortisol/prolactin profile — most modern protocols prefer ipamorelin for cleaner GH release. If used, it's typically alone or briefly paired with a GHRH analog.
Hexarelin is the most potent ghrelin-receptor secretagogue but elevates cortisol and prolactin and produces rapid receptor desensitization — most clinicians have moved to ipamorelin.
- •Cortisol and prolactin elevation at higher doses — hexarelin is less selective than ipamorelin.
- •Receptor desensitization develops within weeks of continuous use; cycles are short for this reason.
- •Reported side effects: water retention, transient blood pressure changes, joint pain.
- •Not FDA-approved.
- •Active or recent malignancy
- •Untreated hyperprolactinemia
- •Cushing's syndrome or other cortisol disorders
- •Pregnancy or breastfeeding
Hexarelin Dosing FAQ
Most clinicians have moved to ipamorelin for ongoing protocols. Hexarelin still appears in short-cycle, high-potency contexts where its larger single-pulse GH release is the goal. For continuous or maintenance protocols, ipamorelin is the better choice.
Typically 4 weeks before a 4-week break. Receptor desensitization makes longer continuous cycles inefficient.
Sources
Related Dosage Charts
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Mechanism, clinical evidence, side effects, costs, and provider listings for Hexarelin therapy.
See Hexarelin guideMedical Disclaimer: This content is for informational purposes only and should not be considered medical advice. Always consult with a qualified healthcare provider before beginning any peptide therapy treatment.