Peptides for Healing & Recovery — Dosage Comparison
Side-by-side comparison of dose, frequency, route, and best-fit use case across the major recovery peptides.
Educational tool — not medical advice. This calculator provides estimates based on population averages and published trial data. Outputs are not clinical recommendations and do not replace evaluation by a qualified prescriber. Do not start, stop, or change a peptide therapy based on the result of this tool.
Healing peptides are the most heavily searched category in 2026 peptide therapy, driven by tendon, gut, and post-surgical interest. None of the peptides in this category are FDA-approved — all are accessed through 503A/503B compounding pharmacies. The matrix below compares typical dosing across the four most-used recovery peptides plus links to the Wolverine Stack protocol that combines BPC-157 and TB-500.
Side-by-Side Dosage Comparison
| Peptide | Status | Typical dose | Frequency | Route | Cycle | Best for | Chart |
|---|---|---|---|---|---|---|---|
| BPC-157 | Compounded (503A/503B) | 200–500 mcg/day | 1–2× daily | subQ or oral | 4–8 weeks | Tendon, ligament, gut (oral), post-surgical recovery. Most flexible recovery peptide. | View |
| TB-500 | Compounded (503A/503B) | 2–2.5 mg loading; 2 mg maintenance | 2× weekly loading; 1× weekly maintenance | subQ (systemic) | 4–6 weeks loading + 4–6 weeks maintenance | Soft-tissue and tendon injuries; broader regeneration. WADA-banned for athletes. | View |
| GHK-Cu | Compounded (503A/503B) | Topical 0.05–2%; injectable 1–2 mg | Topical 1–2× daily; injectable daily | Topical or subQ | Topical continuous; injectable 4–6 weeks | Skin, hair, and tissue repair. Topical use has the strongest evidence. | View |
| KPV | Compounded (503A/503B) | 250–500 mcg/day | 1–2× daily | Oral or subQ | 4–6 weeks | Gut inflammation (IBD/IBS), often stacked with BPC-157. | View |
Who this is for
Patients with chronic tendinopathy, partial-thickness tendon tears, post-surgical recovery, IBD/IBS, or skin/hair concerns who are working with a qualified provider through a 503A/503B compounding pharmacy. Best as an adjunct to physical therapy, dietary intervention, or topical care — not as a substitute for those primary treatments.
Who should avoid
Anyone with active or recent malignancy (relative contraindication for most peptides in this category due to angiogenic and pro-migratory mechanisms). Pregnant or breastfeeding patients. Athletes under WADA-aligned testing should specifically avoid TB-500. Patients without provider supervision and a legitimate compounding pharmacy source.
Stack Protocols for This Therapy
Healing & Recovery Peptides Dosing FAQ
BPC-157 is the most flexible entry point — it can be administered orally for gut indications or subcutaneously for tendon and systemic use. For severe soft-tissue injuries, the Wolverine Stack (BPC-157 + TB-500) is the more aggressive option. For skin and hair, topical GHK-Cu has the strongest evidence base.
Most practitioners specifically pair peptide therapy with physical therapy because tendon remodeling responds to controlled mechanical stress. NSAID co-use is generally fine for short courses but high-dose chronic NSAIDs can blunt the inflammatory signaling that healing peptides are intended to leverage.
Gut and inflammation symptoms commonly improve in 1–2 weeks. Tendon and ligament responses typically emerge over 3–6 weeks. The standard 4–8 week cycle is built around the slow tendon-remodeling timeline.
No. BPC-157, TB-500, GHK-Cu (injectable), and KPV are all compounded, not FDA-approved. Topical GHK-Cu cosmetic formulations are widely sold but are regulated as cosmetics rather than as approved drugs.
Sources
Medical Disclaimer: This content is for informational purposes only and should not be considered medical advice. Always consult with a qualified healthcare provider before beginning any peptide therapy treatment.