Selank Dosage Chart
Clinic/vendor intranasal protocol and source limits for the Russian-approved anxiolytic peptide.
Fact-checking at PeptideProbe is editorial, not clinical. Our editors check claims, dosing figures, and trial results against primary sources; they are not licensed clinicians and do not provide medical review. Nothing here is medical advice — talk to a qualified healthcare provider before starting any therapy.
Educational tool — not medical advice. This calculator provides estimates based on population averages and published trial data. Outputs are not clinical recommendations and do not replace evaluation by a qualified prescriber. Do not start, stop, or change a peptide therapy based on the result of this tool.
Selank is a synthetic analog of tuftsin developed at Russia's Institute of Molecular Genetics. It is Russian-approved as an anxiolytic with anti-asthenic and cognitive-supportive effects. Russian clinical literature describes an anxiolytic profile distinct from benzodiazepines, but Western replication is limited. It is not FDA-approved in the US and was not one of the seven substances considered at the July 23-24, 2026 PCAC meeting.
Selank at a Glance
| Clinic/vendor dose | 250–500 mcg per nostril (total 500–1,000 mcg per dose) |
|---|---|
| Frequency | 2–3× per day intranasal |
| Cycle length | 2–4 weeks per cycle (not source-derived) |
| Route | Intranasal spray |
| FDA status | Not FDA-approved. Russian-approved; not considered at the July 2026 PCAC meeting. |
| Source quality | One Russian-language clinical study; no English replicated dose-ranging trial. |
Selank Dosing by Use Case
Commonly cited protocols vary by what Selank is being used for. The table below summarizes typical ranges reported in clinical practice and published literature.
| Use case | Typical dose | Frequency | Cycle length | Notes |
|---|---|---|---|---|
| Anxiety / asthenic states | 500–1,000 mcg total per dose | 2–3× daily intranasal | 2–4 weeks | Common clinic/vendor convention; not established by the cited PubMed source. |
| Cognitive support | 500 mcg total per dose | 2× daily intranasal | 2–3 weeks | Lower-dose clinic/vendor convention for memory and focus support. |
Stacking Selank
Selank is sometimes paired with Semax (another Russian-approved nasal peptide) for combined anxiolytic + nootropic effect. The two are typically alternated rather than co-administered to minimize receptor overlap.
Where these numbers come from
The cited Selank source is a Russian-language clinical study in generalized anxiety disorder and neurasthenia comparing Selank with medazepam and discussing possible enkephalin-related mechanisms. It supports that Selank has published clinical literature for anxiolytic use, but it does not establish the specific 250-500 mcg per nostril, 2-3x daily, 2-4 week protocol printed here. Those doses and cycle lengths are clinic and vendor convention, not FDA-labeled dosing and not independently replicated in English-language journals. Selank is approved in Russia but not FDA-approved in the US, and it was not one of the seven substances considered at the July 23-24, 2026 PCAC meeting.
Selank has limited Russian clinical safety data and sparse Western validation.
- •Common side effects: minimal — mild nasal irritation is the most reported.
- •Russian-language reports do not establish a benzodiazepine-like dependence or withdrawal pattern, but long-term safety data remain limited.
- •Long-term use beyond 4 weeks per cycle is not well-characterized.
- •Not FDA-approved.
- •Pregnancy or breastfeeding
- •Active sinusitis or nasal pathology (avoid intranasal route)
Selank Dosing FAQ
Selank is described as anxiolytic without the GABAergic sedative profile expected of benzodiazepines, based mainly on Russian clinical literature. Western validation is limited, and dependence or withdrawal claims should be treated cautiously.
Clinic protocols often describe effects over hours to days and use 2–4 week courses rather than single-dose use. The specific consumer dosing schedule is not established by the cited PubMed source.
Sources
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Medical Disclaimer: This content is for informational purposes only and should not be considered medical advice. Always consult with a qualified healthcare provider before beginning any peptide therapy treatment.