Approved outside the US

Selank Dosage Chart

Intranasal protocol (250–500 mcg per nostril, 2–3× daily) and cycle length for the Russian-approved anxiolytic peptide.

Written by
Megan Williams
Editor-in-Chief
Reviewed by
Brian Williams
Co-founder & Research Editor
Last updated
April 25, 2026

Educational tool — not medical advice. This calculator provides estimates based on population averages and published trial data. Outputs are not clinical recommendations and do not replace evaluation by a qualified prescriber. Do not start, stop, or change a peptide therapy based on the result of this tool.

Selank is a synthetic analog of tuftsin developed at Russia's Institute of Molecular Genetics. It is Russian-approved as an anxiolytic with anti-asthenic and cognitive-supportive effects. Unlike benzodiazepines, it does not produce sedation, dependence, or withdrawal in published trial data. It is not FDA-approved in the US.

Selank at a Glance

Typical dose250–500 mcg per nostril (total 500–1,000 mcg per dose)
Frequency2–3× per day intranasal
Cycle length2–4 weeks per cycle
RouteIntranasal spray
FDA statusNot FDA-approved (US). Russian-approved anxiolytic.
Source qualityRussian clinical trial data; limited Western validation.

Selank Dosing by Use Case

Commonly cited protocols vary by what Selank is being used for. The table below summarizes typical ranges reported in clinical practice and published literature.

Use caseTypical doseFrequencyCycle lengthNotes
Anxiety / asthenic states500–1,000 mcg total per dose2–3× daily intranasal2–4 weeksStandard Russian-protocol use case. Pulse-cycle rather than continuous use.
Cognitive support500 mcg total per dose2× daily intranasal2–3 weeksLower-dose protocol for memory and focus support.

Stacking Selank

Selank is sometimes paired with Semax (another Russian-approved nasal peptide) for combined anxiolytic + nootropic effect. The two are typically alternated rather than co-administered to minimize receptor overlap.

Safety profile

Selank has a clean published safety profile in Russian trials but lacks Western validation.

  • Common side effects: minimal — mild nasal irritation is the most reported.
  • Does not produce sedation, dependence, or withdrawal in published trial data.
  • Long-term use beyond 4 weeks per cycle is not well-characterized.
  • Not FDA-approved.
Do not use if
  • Pregnancy or breastfeeding
  • Active sinusitis or nasal pathology (avoid intranasal route)

Selank Dosing FAQ

Selank produces anxiolytic effects without GABAergic sedation, dependence, or withdrawal — at least according to Russian trial data. It does not impair cognition or motor performance the way benzodiazepines can. Western validation is limited but the pharmacology is mechanistically distinct.

Acute anxiolytic effects are reported within hours to days of starting; the published Russian protocol is a 2–4 week course rather than a single dose.

Sources

Related Dosage Charts

Want the full Selank guide?

Mechanism, clinical evidence, side effects, costs, and provider listings for Selank therapy.

See Selank guide

Medical Disclaimer: This content is for informational purposes only and should not be considered medical advice. Always consult with a qualified healthcare provider before beginning any peptide therapy treatment.